Influenza Virus Genomic Surveillance, Arizona, USA, 2023–2024

Rabia Maqsood, Matthew F. Smith, La Rinda A. Holland, Regan A. Sullins, Steven C. Holland, Michelle Tan, Gabrielle M. Hernandez Barrera, Alexis W. Thomas, Mario Islas, Joanna L. Kramer, Lora Nordstrom, Mary Mulrow, Michael White, Vel Murugan, Efrem S. Lim

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Influenza viruses are constantly evolving and are therefore monitored worldwide in the hope to reduce the burden of disease by annual updates to vaccine recommendations. We conducted genomic sequencing of 110 influenza A and 30 influenza B viruses from specimens collected between October 2023 and February 2024 in Arizona, USA. We identified mutations in the hemagglutinin (HA) antigenic sites as well as the neuraminidase (NA) gene in our samples. We also found no unique HA and NA mutations in vaccinated yet influenza-infected individuals. Real-time genomic sequencing surveillance is important to ensure influenza vaccine effectiveness.

Original languageEnglish (US)
Article number692
JournalViruses
Volume16
Issue number5
DOIs
StatePublished - May 2024

Keywords

  • Arizona
  • genomic surveillance
  • influenza virus

ASJC Scopus subject areas

  • Infectious Diseases
  • Virology

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