Immunosignaturing: A critical review

Kathryn F. Sykes; Joseph B. Legutki; Phillip Stafford

doi:10.1016/j.tibtech.2012.10.012

Immunosignaturing: A critical review

Kathryn F. Sykes, Joseph B. Legutki, Phillip Stafford

Research output: Contribution to journal › Review article › peer-review

47 Scopus citations

Abstract

Health is a complex interaction between metabolism, physiology, and immunity. Although it is difficult to define quantitatively, the activity of the humoral immune system provides a reasonable proxy for changes in health. Immunosignaturing is a microarray-based technology that quantitates the dynamics of circulating antibodies. Recent advancements in the field warrant a review of the technology. Here, we provide an introduction to the technique, evaluate the current progress, contrast similar technologies, and suggest applications that immunosignaturing could facilitate.

Original language	English (US)
Pages (from-to)	45-51
Number of pages	7
Journal	Trends in Biotechnology
Volume	31
Issue number	1
DOIs	https://doi.org/10.1016/j.tibtech.2012.10.012
State	Published - Jan 1 2013

Keywords

Antibody profiling
Biomarker discovery
Health monitoring
Immunodiagnostics
Peptide microarray

ASJC Scopus subject areas

Biotechnology
Bioengineering

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10.1016/j.tibtech.2012.10.012

Cite this

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KW - Health monitoring

KW - Immunodiagnostics

KW - Peptide microarray

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Immunosignaturing: A critical review

Abstract

Keywords

ASJC Scopus subject areas

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