Immunosignaturing: A critical review

Kathryn F. Sykes, Joseph B. Legutki, Phillip Stafford

Research output: Contribution to journalReview articlepeer-review

47 Scopus citations


Health is a complex interaction between metabolism, physiology, and immunity. Although it is difficult to define quantitatively, the activity of the humoral immune system provides a reasonable proxy for changes in health. Immunosignaturing is a microarray-based technology that quantitates the dynamics of circulating antibodies. Recent advancements in the field warrant a review of the technology. Here, we provide an introduction to the technique, evaluate the current progress, contrast similar technologies, and suggest applications that immunosignaturing could facilitate.

Original languageEnglish (US)
Pages (from-to)45-51
Number of pages7
JournalTrends in Biotechnology
Issue number1
StatePublished - Jan 1 2013


  • Antibody profiling
  • Biomarker discovery
  • Health monitoring
  • Immunodiagnostics
  • Peptide microarray

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering


Dive into the research topics of 'Immunosignaturing: A critical review'. Together they form a unique fingerprint.

Cite this