High performance liquid chromatographic separation of bryostatins 1–12

George Pettit, Y. Kamano, D. Schaufelberger, C. L. Herald, P. M. Blumberg, S. W. May

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


A reversed-phase high performance liquid chromatographic (RP-8; acetonitrile-water gradient) separation procedure was developed for detecting bryostatins 1–12, using a photodiode array detector system. While bryostatins 6 and 9 were found to co-elute they were easily separated using a silica gel column with 9:1 n-hexane-n-propanol as eluent.

Original languageEnglish (US)
Pages (from-to)553-561
Number of pages9
JournalJournal of Liquid Chromatography
Issue number4
StatePublished - Jan 3 1989

ASJC Scopus subject areas

  • Molecular Medicine


Dive into the research topics of 'High performance liquid chromatographic separation of bryostatins 1–12'. Together they form a unique fingerprint.

Cite this