Gas dynamic virtual nozzle for generation of microscopic droplet streams

D. P. DePonte; Uwe Weierstall; Kevin Schmidt; J. Warner; D. Starodub; John Spence; R. B. Doak

doi:10.1088/0022-3727/41/19/195505

Gas dynamic virtual nozzle for generation of microscopic droplet streams

D. P. DePonte, Uwe Weierstall, Kevin Schmidt, J. Warner, D. Starodub, John Spence, R. B. Doak

Physics

Research output: Contribution to journal › Article › peer-review

418 Scopus citations

Abstract

As shown by Gãn-Calvo (1998 Phys. Rev. Lett. 80 285-8), a free liquid jet can be compressed in diameter through gas dynamic forces exerted by a coaxially co-flowing gas, obviating the need for a solid nozzle to form a microscopic liquid jet and thereby alleviating the clogging problems that plague conventional droplet sources of small diameter. We describe in this paper a novel form of droplet beam source based on this principle. The source is miniature, robust, dependable, easily fabricated, essentially immune to clogging and eminently suitable for delivery of microscopic liquid droplets, including hydrated biological samples, into vacuum for analysis using vacuum instrumentation. Monodisperse, single-file droplet streams are generated by triggering the device with a piezoelectric actuator.

Original language	English (US)
Article number	195505
Journal	Journal of Physics D: Applied Physics
Volume	41
Issue number	19
DOIs	https://doi.org/10.1088/0022-3727/41/19/195505
State	Published - Oct 7 2008

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Acoustics and Ultrasonics
Surfaces, Coatings and Films

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10.1088/0022-3727/41/19/195505

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abstract = "As shown by G{\~a}n-Calvo (1998 Phys. Rev. Lett. 80 285-8), a free liquid jet can be compressed in diameter through gas dynamic forces exerted by a coaxially co-flowing gas, obviating the need for a solid nozzle to form a microscopic liquid jet and thereby alleviating the clogging problems that plague conventional droplet sources of small diameter. We describe in this paper a novel form of droplet beam source based on this principle. The source is miniature, robust, dependable, easily fabricated, essentially immune to clogging and eminently suitable for delivery of microscopic liquid droplets, including hydrated biological samples, into vacuum for analysis using vacuum instrumentation. Monodisperse, single-file droplet streams are generated by triggering the device with a piezoelectric actuator.",

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AU - DePonte, D. P.

AU - Weierstall, Uwe

AU - Schmidt, Kevin

AU - Warner, J.

AU - Starodub, D.

AU - Spence, John

AU - Doak, R. B.

PY - 2008/10/7

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Gas dynamic virtual nozzle for generation of microscopic droplet streams

Abstract

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