Emerging roles of β-arrestins

F. Gregory Buchanan; Raymond N. DuBois

doi:10.4161/cc.5.18.3212

Emerging roles of β-arrestins

F. Gregory Buchanan
, Raymond N. DuBois

Research output: Contribution to journal › Review article › peer-review

36 Scopus citations

Abstract

Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for β-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.

Original language	English (US)
Pages (from-to)	2060-2063
Number of pages	4
Journal	Cell Cycle
Volume	5
Issue number	18
DOIs	https://doi.org/10.4161/cc.5.18.3212
State	Published - Sep 15 2006
Externally published	Yes

Keywords

Arrestin
B-Arrestin
Development
EGFR
Metastasis
Migration
Nuclear
Review
Src
Wnt

ASJC Scopus subject areas

Molecular Biology
Developmental Biology
Cell Biology

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10.4161/cc.5.18.3212

Cite this

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abstract = "Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for β-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.",

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AU - DuBois, Raymond N.

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AB - Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for β-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.

KW - Arrestin

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KW - Development

KW - EGFR

KW - Metastasis

KW - Migration

KW - Nuclear

KW - Review

KW - Src

KW - Wnt

UR - https://www.scopus.com/pages/publications/33749652386

UR - https://www.scopus.com/pages/publications/33749652386#tab=citedBy

U2 - 10.4161/cc.5.18.3212

DO - 10.4161/cc.5.18.3212

M3 - Review article

C2 - 16969081

AN - SCOPUS:33749652386

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SP - 2060

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JO - Cell Cycle

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ER -

Emerging roles of β-arrestins

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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