DNA tile based self-assembly: Building complex nanoarchitectures

Chenxiang Lin, Yan Liu, Sherri Rinker, Hao Yan

Research output: Contribution to journalShort surveypeer-review

341 Scopus citations


DNA tile based self-assembly provides an attractive route to create nanoarchitectures of programmable patterns. It also offers excellent scaffolds for directed self-assembly of nanometer-scale materials, ranging from nanoparticles to proteins, with potential applications in constructing nanoelectronic/nanophotonic devices and protein/ligand nanoarrays. This Review first summarizes the currently available DNA tile toolboxes and further emphasizes recent developments toward self-assembling DNA nanostructures with increasing complexity. Exciting progress using DNA tiles for directed self-assembly of other nanometer scale components is also discussed.

Original languageEnglish (US)
Pages (from-to)1641-1647
Number of pages7
Issue number8
StatePublished - Aug 11 2006


  • DNA structures
  • Nanostructures
  • Nanotechnology
  • Self-assembly
  • Structure elucidation

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Physical and Theoretical Chemistry


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