Differential effects of assisted cycling therapy on short-term and working memory of adolescents with Down syndrome

Simon D. Holzapfel; Shannon Ringenbach; Genna M. Mulvey; Amber M. Sandoval-Menendez; Natasha Birchfield; Shreja R. Tahiliani

doi:10.1080/20445911.2016.1205592

Differential effects of assisted cycling therapy on short-term and working memory of adolescents with Down syndrome

Simon D. Holzapfel, Shannon Ringenbach, Genna M. Mulvey, Amber M. Sandoval-Menendez, Natasha Birchfield, Shreja R. Tahiliani

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Persons with Down syndrome (DS) suffer from prefrontal cortex dysfunction and deficits in executive functions. The current study examined the effects assisted cycling therapy (ACT) on short-term (STM) and working memory (WM) in adolescents with DS. During ACT, the cadence of participants on a stationary bicycle was augmented with an electrical motor to 180% of the voluntary cadence. Participants completed eight weeks of ACT (n = 17), eight weeks of voluntary cycling (VC) at their own preferred cadence (n = 16), or eight weeks of no cycling (np ≥.149) and working memory improved only in the ACT group (Hedge’s g = 1.66; p =.003). The results indicate that assisted high-cadence cycling (i.e. ACT) produces superior neural benefits in the dorsolateral prefrontal cortex compared to VC.

Original language	English (US)
Pages (from-to)	990-1003
Number of pages	14
Journal	Journal of Cognitive Psychology
Volume	28
Issue number	8
DOIs	https://doi.org/10.1080/20445911.2016.1205592
State	Published - Nov 16 2016

Keywords

Prefrontal cortex
aerobic exercise
cortical activation
executive function
neurotrophic factors

ASJC Scopus subject areas

Experimental and Cognitive Psychology

Access to Document

10.1080/20445911.2016.1205592

Cite this

@article{a026964639fa4d939eeba1dde8c3f9a7,

title = "Differential effects of assisted cycling therapy on short-term and working memory of adolescents with Down syndrome",

abstract = "Persons with Down syndrome (DS) suffer from prefrontal cortex dysfunction and deficits in executive functions. The current study examined the effects assisted cycling therapy (ACT) on short-term (STM) and working memory (WM) in adolescents with DS. During ACT, the cadence of participants on a stationary bicycle was augmented with an electrical motor to 180% of the voluntary cadence. Participants completed eight weeks of ACT (n = 17), eight weeks of voluntary cycling (VC) at their own preferred cadence (n = 16), or eight weeks of no cycling (np ≥.149) and working memory improved only in the ACT group (Hedge{\textquoteright}s g = 1.66; p =.003). The results indicate that assisted high-cadence cycling (i.e. ACT) produces superior neural benefits in the dorsolateral prefrontal cortex compared to VC.",

keywords = "Prefrontal cortex, aerobic exercise, cortical activation, executive function, neurotrophic factors",

author = "Holzapfel, {Simon D.} and Shannon Ringenbach and Mulvey, {Genna M.} and Sandoval-Menendez, {Amber M.} and Natasha Birchfield and Tahiliani, {Shreja R.}",

note = "Funding Information: This work was supported by the National Institute of Child Health and Human Development under Grant 5R03HD073652-02. Publisher Copyright: {\textcopyright} 2016 Informa UK Limited, trading as Taylor & Francis Group. Copyright: Copyright 2016 Elsevier B.V., All rights reserved.",

year = "2016",

month = nov,

day = "16",

doi = "10.1080/20445911.2016.1205592",

language = "English (US)",

volume = "28",

pages = "990--1003",

journal = "Journal of Cognitive Psychology",

issn = "2044-5911",

publisher = "Psychology Press Ltd",

number = "8",

}

TY - JOUR

T1 - Differential effects of assisted cycling therapy on short-term and working memory of adolescents with Down syndrome

AU - Holzapfel, Simon D.

AU - Ringenbach, Shannon

AU - Mulvey, Genna M.

AU - Sandoval-Menendez, Amber M.

AU - Birchfield, Natasha

AU - Tahiliani, Shreja R.

N1 - Funding Information: This work was supported by the National Institute of Child Health and Human Development under Grant 5R03HD073652-02. Publisher Copyright: © 2016 Informa UK Limited, trading as Taylor & Francis Group. Copyright: Copyright 2016 Elsevier B.V., All rights reserved.

PY - 2016/11/16

Y1 - 2016/11/16

N2 - Persons with Down syndrome (DS) suffer from prefrontal cortex dysfunction and deficits in executive functions. The current study examined the effects assisted cycling therapy (ACT) on short-term (STM) and working memory (WM) in adolescents with DS. During ACT, the cadence of participants on a stationary bicycle was augmented with an electrical motor to 180% of the voluntary cadence. Participants completed eight weeks of ACT (n = 17), eight weeks of voluntary cycling (VC) at their own preferred cadence (n = 16), or eight weeks of no cycling (np ≥.149) and working memory improved only in the ACT group (Hedge’s g = 1.66; p =.003). The results indicate that assisted high-cadence cycling (i.e. ACT) produces superior neural benefits in the dorsolateral prefrontal cortex compared to VC.

AB - Persons with Down syndrome (DS) suffer from prefrontal cortex dysfunction and deficits in executive functions. The current study examined the effects assisted cycling therapy (ACT) on short-term (STM) and working memory (WM) in adolescents with DS. During ACT, the cadence of participants on a stationary bicycle was augmented with an electrical motor to 180% of the voluntary cadence. Participants completed eight weeks of ACT (n = 17), eight weeks of voluntary cycling (VC) at their own preferred cadence (n = 16), or eight weeks of no cycling (np ≥.149) and working memory improved only in the ACT group (Hedge’s g = 1.66; p =.003). The results indicate that assisted high-cadence cycling (i.e. ACT) produces superior neural benefits in the dorsolateral prefrontal cortex compared to VC.

KW - Prefrontal cortex

KW - aerobic exercise

KW - cortical activation

KW - executive function

KW - neurotrophic factors

UR - http://www.scopus.com/inward/record.url?scp=84978938300&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84978938300&partnerID=8YFLogxK

U2 - 10.1080/20445911.2016.1205592

DO - 10.1080/20445911.2016.1205592

M3 - Article

AN - SCOPUS:84978938300

SN - 2044-5911

VL - 28

SP - 990

EP - 1003

JO - Journal of Cognitive Psychology

JF - Journal of Cognitive Psychology

IS - 8

ER -

Differential effects of assisted cycling therapy on short-term and working memory of adolescents with Down syndrome

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this