Dietary models of insulin resistance

James Deer; Juraj Koska; Marlies Ozias; Peter Reaven

doi:10.1016/j.metabol.2014.08.013

Dietary models of insulin resistance

James Deer, Juraj Koska, Marlies Ozias, Peter Reaven

Research output: Contribution to journal › Review article › peer-review

44 Scopus citations

Abstract

Insulin resistance is a significant factor in the development of type 2 diabetes mellitus, however the connection between the Western diet and the development of insulin resistance has not been fully explained. Dietary macronutrient composition has been examined in a number of articles, and diets enriched in saturated fatty acids, and possibly in fructose, appear to be most consistently associated with the development of insulin resistance. However, mechanistic insights into the metabolic effects of such diets are lacking, and merit further study.

Original language	English (US)
Pages (from-to)	163-171
Number of pages	9
Journal	Metabolism: Clinical and Experimental
Volume	64
Issue number	2
DOIs	https://doi.org/10.1016/j.metabol.2014.08.013
State	Published - Feb 1 2015
Externally published	Yes

Keywords

Carbohydrate
Dietary composition
Fat
Insulin resistance

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

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10.1016/j.metabol.2014.08.013

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AB - Insulin resistance is a significant factor in the development of type 2 diabetes mellitus, however the connection between the Western diet and the development of insulin resistance has not been fully explained. Dietary macronutrient composition has been examined in a number of articles, and diets enriched in saturated fatty acids, and possibly in fructose, appear to be most consistently associated with the development of insulin resistance. However, mechanistic insights into the metabolic effects of such diets are lacking, and merit further study.

KW - Carbohydrate

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KW - Fat

KW - Insulin resistance

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Dietary models of insulin resistance

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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