Dietary models of insulin resistance

James Deer, Juraj Koska, Marlies Ozias, Peter Reaven

Research output: Contribution to journalReview articlepeer-review

44 Scopus citations


Insulin resistance is a significant factor in the development of type 2 diabetes mellitus, however the connection between the Western diet and the development of insulin resistance has not been fully explained. Dietary macronutrient composition has been examined in a number of articles, and diets enriched in saturated fatty acids, and possibly in fructose, appear to be most consistently associated with the development of insulin resistance. However, mechanistic insights into the metabolic effects of such diets are lacking, and merit further study.

Original languageEnglish (US)
Pages (from-to)163-171
Number of pages9
JournalMetabolism: Clinical and Experimental
Issue number2
StatePublished - Feb 1 2015
Externally publishedYes


  • Carbohydrate
  • Dietary composition
  • Fat
  • Insulin resistance

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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