Blood supply and safety in the developing world: Considerations for emerging markets

William Riley, Jeffry McCullough

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Assuring a safe and adequate blood supply in developing nations such as emerging markets is a daunting challenge that directly affects fundamental health metrics of a country. Numerous mortalities can be reduced when an effective national blood transfusion system is in place. These mortalities include leading causes of death such as maternal hemorrhage, sickle cell anemia, and malaria. There exists a circular relationship between blood supply and safety: efforts to ensure donor and recipient safety reduce the population of eligible voluntary blood donors, which in turn restricts blood supply. In this article we describe the main issues for blood supply in developing nations and emerging markets, identify the major causes and impact of transfusion transmitted infections, present a safety model that describes the relationship between defensive barriers in depth to assure safe blood, its effectiveness, and the impact it has on safe blood supply. The results of this study apply to the forty seven nations sub-Saharan Africa (SSA) based on an extrapolation from a focused analysis on twenty two African countries. Finally, we discuss strategies for blood safety and supply in developing nations.

Original languageEnglish (US)
Pages (from-to)50-57
Number of pages8
JournalJournal of Commercial Biotechnology
Issue number4
StatePublished - Oct 1 2012
Externally publishedYes


  • Blood supply
  • Developing countries
  • Emerging markets
  • Patient safety

ASJC Scopus subject areas

  • Biotechnology
  • Economics and Econometrics
  • Management of Technology and Innovation


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