Assessing the need for a standardized cancer Human Biobank (caHUB): Findings from a national survey with cancer researchers

Holly A. Massett, Nancy L. Atkinson, Deanne Weber, Renate Myles, Colleen Ryan, Meredith Grady, Carolyn Compton

Research output: Contribution to journalArticlepeer-review

58 Scopus citations


Background: Before developing a national standardized cancer HUman Biobank (caHUB), the National Cancer Institute sought feedback from the cancer research community. Methods: NCI conducted an online survey (N = 727) about current biospecimen needs and reactions to creating a national resource cancer researchers and others. Results: Most (56%) participants obtained biospecimens within their own institutions, and 63% wanted more information about their biospecimens. Large proportions reported difficulty obtaining biospecimens of adequate numbers (39%) and quality (47%). Low-quality biospecimens resulted in 60% questioning their findings and 81% limiting the scope of their work. Nine in every 10 (91.3%) respondents reacted positively to the idea of a national biospecimen resource, with 62% reporting that they would obtain biospecimens from it and 53% reporting that they would be willing to contribute biospecimens to it. Conclusions: Initial reactions to caHUB were positive and seen as a feasible option to addressing respondents' research challenges. National Cancer Institute will need to address several concerns to assure its adoption, including standardization and sustainability. Published by Oxford University Press 2011.

Original languageEnglish (US)
Pages (from-to)8-15
Number of pages8
JournalJournal of the National Cancer Institute - Monographs
Issue number42
StatePublished - 2011
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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