Antigen Delivery System II: Development of Live Attenuated Bacterial Vectors

Roy Curtiss

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations


This chapter reviews papers mostly written since 2005 that report results using live attenuated bacterial vectors to deliver after administration through mucosal surfaces, protective antigens, and DNA vaccines, encoding protective antigens to induce immune responses and/or protective immunity to pathogens that colonize on or invade through mucosal surfaces. Papers that report use of such vaccine vector systems for parenteral vaccination or to deal with nonmucosal pathogens or do not address induction of mucosal antibody and/or cellular immune responses are not reviewed.

Original languageEnglish (US)
Title of host publicationMucosal Immunology
Subtitle of host publicationFourth Edition
PublisherElsevier Inc.
Number of pages37
ISBN (Electronic)9780124159754
ISBN (Print)9780124158474
StatePublished - Apr 1 2015


  • Antigen delivery
  • Attenuation
  • DNA vaccine
  • Lactobacillus
  • Mucosal associated lymphoid tissue (MALT)
  • Mucosal immunity
  • Mutation
  • Plasmid
  • Salmonella
  • Sublingual immunization

ASJC Scopus subject areas

  • General Medicine
  • General Immunology and Microbiology


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