Alteration of gonococcal protein expression in acidic culture

Robin K. Pettit, Melanie J. Filiatrault, Elda S. Martin

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


We grew Neisseria gonorrhoeae under acidic, neutral, and alkaline conditions and noted altered expression of at least 12 outer membrane proteins between 31 and 100 kDa in size. One protein whose expression was upregulated under acidic conditions was gonococcal heat shock protein 63. These proteins may contribute to the pathogenesis of gonorrhea in the urogenital tract.

Original languageEnglish (US)
Pages (from-to)1039-1042
Number of pages4
JournalInfection and immunity
Issue number3
StatePublished - 1996
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases


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