Adult ovary transfer counteracts the callosal enlargement resulting from prepubertal ovariectomy

Heather A. Bimonte; R. Holly Fitch; Victor H. Denenberg

doi:10.1016/S0006-8993(00)02505-1

Adult ovary transfer counteracts the callosal enlargement resulting from prepubertal ovariectomy

Heather A. Bimonte, R. Holly Fitch, Victor H. Denenberg

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

The rat corpus callosum (CC) is larger in males than females, and is sensitive to hormone manipulations during development. Previous research found that, in rats, CC sensitivity to testosterone ended by postnatal day 8 (P8). In contrast, more recent findings demonstrated that CC responsivity to ovarian hormones continued at least through P70. The current experiment extends these findings by showing that the female callosum is still sensitive to ovarian hormones as late as P130, well into adulthood. (C) 2000 Elsevier Science B.V.

Original language	English (US)
Pages (from-to)	254-257
Number of pages	4
Journal	Brain Research
Volume	872
Issue number	1-2
DOIs	https://doi.org/10.1016/S0006-8993(00)02505-1
State	Published - Jul 28 2000
Externally published	Yes

Keywords

Corpus callosum
Feminization
Organizational effects
Ovarian hormones
Sexual differentiation

ASJC Scopus subject areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

Access to Document

10.1016/S0006-8993(00)02505-1

Cite this

@article{d15e7070aff443e7bdd78e2131df3940,

title = "Adult ovary transfer counteracts the callosal enlargement resulting from prepubertal ovariectomy",

abstract = "The rat corpus callosum (CC) is larger in males than females, and is sensitive to hormone manipulations during development. Previous research found that, in rats, CC sensitivity to testosterone ended by postnatal day 8 (P8). In contrast, more recent findings demonstrated that CC responsivity to ovarian hormones continued at least through P70. The current experiment extends these findings by showing that the female callosum is still sensitive to ovarian hormones as late as P130, well into adulthood. (C) 2000 Elsevier Science B.V.",

keywords = "Corpus callosum, Feminization, Organizational effects, Ovarian hormones, Sexual differentiation",

author = "Bimonte, {Heather A.} and {Holly Fitch}, R. and Denenberg, {Victor H.}",

year = "2000",

month = jul,

day = "28",

doi = "10.1016/S0006-8993(00)02505-1",

language = "English (US)",

volume = "872",

pages = "254--257",

journal = "Brain Research",

issn = "0006-8993",

publisher = "Elsevier B.V.",

number = "1-2",

}

TY - JOUR

T1 - Adult ovary transfer counteracts the callosal enlargement resulting from prepubertal ovariectomy

AU - Bimonte, Heather A.

AU - Holly Fitch, R.

AU - Denenberg, Victor H.

PY - 2000/7/28

Y1 - 2000/7/28

N2 - The rat corpus callosum (CC) is larger in males than females, and is sensitive to hormone manipulations during development. Previous research found that, in rats, CC sensitivity to testosterone ended by postnatal day 8 (P8). In contrast, more recent findings demonstrated that CC responsivity to ovarian hormones continued at least through P70. The current experiment extends these findings by showing that the female callosum is still sensitive to ovarian hormones as late as P130, well into adulthood. (C) 2000 Elsevier Science B.V.

AB - The rat corpus callosum (CC) is larger in males than females, and is sensitive to hormone manipulations during development. Previous research found that, in rats, CC sensitivity to testosterone ended by postnatal day 8 (P8). In contrast, more recent findings demonstrated that CC responsivity to ovarian hormones continued at least through P70. The current experiment extends these findings by showing that the female callosum is still sensitive to ovarian hormones as late as P130, well into adulthood. (C) 2000 Elsevier Science B.V.

KW - Corpus callosum

KW - Feminization

KW - Organizational effects

KW - Ovarian hormones

KW - Sexual differentiation

UR - http://www.scopus.com/inward/record.url?scp=0034725906&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034725906&partnerID=8YFLogxK

U2 - 10.1016/S0006-8993(00)02505-1

DO - 10.1016/S0006-8993(00)02505-1

M3 - Article

C2 - 10924704

AN - SCOPUS:0034725906

SN - 0006-8993

VL - 872

SP - 254

EP - 257

JO - Brain Research

JF - Brain Research

IS - 1-2

ER -

Adult ovary transfer counteracts the callosal enlargement resulting from prepubertal ovariectomy

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this