Networks-on-Chip (NoC) has been proposed as a solution for addressing the design challenges of future high-performance nanoscale architectures. Innovative system-level performance models are required for designing NoC based architectures. This paper presents a VHDL based cycle accurate register transfer level model for evaluating the latency, throughput, dynamic, and leakage power consumption of NoC based interconnection architectures. We implemented a parameterized register transfer level design of the NoC architecture elements. The design is parameterized on (i) size of packets, (ii) length and width of physical links, (Hi) number, and depth of virtual channels, and (iv) switching technique. The paper discusses in detail the architecture and characterization of the various NoC components. The paper presents results obtained by application of the model towards design space exploration, and power versus performance trade-off analysis of 4×4 mesh based NoC architecture.