Abstract
A deterministic model for the transmission dynamics of two strains of an epidemic in the presence of a preventive vaccine is considered. Theoretical results on the existence and stability of the associated equilibria of the model are given. A robust, positivity-preserving, non-standard finite-difference scheme, having the same qualitative features as the continuous model, is constructed. The theoretical and numerical analyses of the model enable the determination of a threshold level of vaccination coverage needed for community-wide eradication of the epidemic.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1037-1051 |
| Number of pages | 15 |
| Journal | Journal of Difference Equations and Applications |
| Volume | 9 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 1 2003 |
| Externally published | Yes |
Keywords
- Basic reproductive number
- Epidemic model
- Mickens-type discretization
- Preventive vaccine
ASJC Scopus subject areas
- Analysis
- Algebra and Number Theory
- Applied Mathematics
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