A new method for the synthesis of nitriles from amides under non-acidic conditions

Marcos L. Sznaidman; Curtis Crasto; Sidney M. Hecht

doi:10.1016/0040-4039(93)85012-L

A new method for the synthesis of nitriles from amides under non-acidic conditions

Marcos L. Sznaidman, Curtis Crasto, Sidney M. Hecht

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Aryl carboxamides and other electron rich amides were converted to the respective nitriles in good yields by treatment with Ag₂O and C₂H₅I in benzene at reflux.

Original language	English (US)
Pages (from-to)	1581-1584
Number of pages	4
Journal	Tetrahedron Letters
Volume	34
Issue number	10
DOIs	https://doi.org/10.1016/0040-4039(93)85012-L
State	Published - Mar 5 1993
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(93)85012-L

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title = "A new method for the synthesis of nitriles from amides under non-acidic conditions",

abstract = "Aryl carboxamides and other electron rich amides were converted to the respective nitriles in good yields by treatment with Ag2O and C2H5I in benzene at reflux.",

author = "Sznaidman, {Marcos L.} and Curtis Crasto and Hecht, {Sidney M.}",

year = "1993",

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language = "English (US)",

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T1 - A new method for the synthesis of nitriles from amides under non-acidic conditions

AU - Sznaidman, Marcos L.

AU - Crasto, Curtis

AU - Hecht, Sidney M.

PY - 1993/3/5

Y1 - 1993/3/5

N2 - Aryl carboxamides and other electron rich amides were converted to the respective nitriles in good yields by treatment with Ag2O and C2H5I in benzene at reflux.

AB - Aryl carboxamides and other electron rich amides were converted to the respective nitriles in good yields by treatment with Ag2O and C2H5I in benzene at reflux.

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U2 - 10.1016/0040-4039(93)85012-L

DO - 10.1016/0040-4039(93)85012-L

M3 - Article

AN - SCOPUS:0027463883

SN - 0040-4039

VL - 34

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 10

ER -

A new method for the synthesis of nitriles from amides under non-acidic conditions

Abstract

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