Research output per year
Research output per year
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Dive into the research topics where Wade Van Horn is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Competition between inside-out unfolding and pathogenic aggregation in an amyloid-forming β-propeller
Saccuzzo, E. G., Mebrat, M. D., Scelsi, H. F., Kim, M., Ma, M. T., Su, X., Hill, S. E., Rheaume, E., Li, R., Torres, M. P., Gumbart, J. C., Van Horn, W. D. & Lieberman, R. L., Dec 2024, In: Nature communications. 15, 1, 155.Research output: Contribution to journal › Article › peer-review
Open Access -
Evidence that the cold- and menthol-sensing functions of the human TRPM8 channel evolved separately
Luu, D. D., Ramesh, N., Can Kazan, I., Shah, K. H., Lahiri, G., Mana, M. D., Banu Ozkan, S. & Van Horn, W. D., Jun 2024, In: Science Advances. 10, 25, eadm9228.Research output: Contribution to journal › Article › peer-review
Open Access -
A molecular perspective on identifying TRPV1 thermosensitive regions and disentangling polymodal activation
Luu, D. D., Owens, A. M., Mebrat, M. D. & Van Horn, W. D., 2023, In: Temperature. 10, 1, p. 67-101 35 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Uracil-DNA glycosylase efficiency is modulated by substrate rigidity
Orndorff, P. B., Poddar, S., Owens, A. M., Kumari, N., Ugaz, B. T., Amin, S., Van Horn, W. D., van der Vaart, A. & Levitus, M., Dec 2023, In: Scientific reports. 13, 1, 3915.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Modeling long QT syndrome type 2 on-a-chip via indepth assessment of isogenic gene-edited 3D cardiac tissues
Veldhuizen, J., Mann, H. F., Karamanova, N., Van Horn, W. D., Migrino, R. Q., Brafman, D. & Nikkhah, M., 2022, In: Science Advances. 8, 50, abq6720.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations
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Planning Study for the Development of Sigma 2 ligands as Analgesics
Van Horn, W. (PI)
HHS: National Institutes of Health (NIH)
9/11/23 → 8/31/25
Project: Research project
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Understanding human TRPV1 polymodal activation
Van Horn, W. (PI) & Singharoy, A. (CoI)
HHS: National Institutes of Health (NIH)
6/15/22 → 4/30/27
Project: Research project
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Molecular Mechanisms and Regulation Networks of TRPM8
Van Horn, W. (PI)
HHS: National Institutes of Health (NIH)
5/1/21 → 2/28/26
Project: Research project
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Comparative study of human and rat TRPV1 transmembrane domain and its role in thermosensing and agonist activation
Van Horn, W. (CoI)
1/1/23 → 12/31/24
Project: Research project
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Characterization of Purified Myocilin: Glaucome as a Protein Misfolding Disease
Van Horn, W. (PI)
HHS: National Institutes of Health (NIH)
3/1/21 → 2/28/25
Project: Research project
Datasets
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2MU4 : Structure of F. tularensis Virulence Determinant
Zook, J. (Contributor), Mo, G. (Contributor), Sisco, N. J. (Contributor), Craciunescu, F. M. (Contributor), Hansen, D. T. (Contributor), Baravati, B. (Contributor), Cherry, B. R. (Contributor), Van Horn, W. D. (Contributor) & Fromme, P. (Contributor), RCSB-PDB, 2015
DOI: 10.2210/pdb2mu4/pdb, https://www.rcsb.org/structure/2MU4
Dataset
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Structural Basis for KCNE3 and Estrogen Modulation of the KCNQ1 Channel
Kroncke, B. M. (Contributor), Van Horn, W. D. (Contributor), Smith, J. (Contributor), Kang, C. (Contributor), Welch, R. C. (Contributor), Song, Y. (Contributor), Nannemann, D. P. (Contributor), Taylor, K. C. (Contributor), Sisco, N. J. (Contributor), George, A. L. (Contributor), Meiler, J. (Contributor), Vanoye, C. G. (Contributor) & Sanders, C. R. (Contributor), Protein Data Bank (PDB), Sep 21 2016
DOI: 10.2210/pdb2NDJ/pdb, https://www.wwpdb.org/pdb?id=pdb_00002ndj
Dataset
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Structure of F. tularensis Virulence Determinant
Zook, J. (Contributor), Mo, G. (Contributor), Sisco, N. J. (Contributor), Craciunescu, F. M. (Contributor), Hansen, D. T. (Contributor), Baravati, B. (Contributor), Cherry, B. R. (Contributor), Sykes, K. (Contributor), Wachter, R. (Contributor), Van Horn, W. D. (Contributor) & Fromme, P. (Contributor), Protein Data Bank (PDB), Jun 10 2015
DOI: 10.2210/pdb2MU4/pdb, https://www.wwpdb.org/pdb?id=pdb_00002mu4
Dataset
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2NDJ : Structural Basis for KCNE3 and Estrogen Modulation of the KCNQ1 Channel
Kroncke, B. M. (Contributor), Van Horn, W. D. (Contributor), Smith, J. (Contributor), Kang, C. (Contributor), Welch, R. C. (Contributor), Song, Y. (Contributor), Nannemann, D. P. (Contributor), Sisco, N. J. (Contributor), George, A. L. (Contributor), Meiler, J. (Contributor), Vanoye, C. G. (Contributor) & Sanders, C. R. (Contributor), RCSB-PDB, 2016
DOI: 10.2210/pdb2ndj/pdb, https://www.rcsb.org/structure/2NDJ
Dataset
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Structure of a new variant of GNCA ancestral beta-lactamase
Modi, T. (Contributor), Risso, V. A. (Contributor), Martinez-Rodriguez, S. (Contributor), Gavira, J. A. (Contributor), Mebrat, M. D. (Contributor), Van Horn, W. D. (Contributor), Sanchez-Ruiz, J. M. (Contributor) & Banu, O. S. (Contributor), Protein Data Bank (PDB), Mar 3 2021
DOI: 10.2210/pdb6YRS/pdb, https://www.wwpdb.org/pdb?id=pdb_00006yrs
Dataset