Expression analysis of Streptomyces avermitilis NRRL8165 delta-aveI mutant

  • Lei Chen (Contributor)
  • Jun Chen (Contributor)
  • Yuqian Jiang (Contributor)
  • Yinhua Lu (Contributor)
  • Weiwen Zhang (Contributor)
  • Weihong Jiang (Contributor)



Investigation of whole genome gene expression level changes in Streptomyces avermitilis delta-aveI mutant, compared to the wild-type strain. The mutants analyzed in this study are further described in Chen L, Lu Y., Chen J, Zhang W, Shu D, Qin Z, Yang S, Jiang W. (2008) Characterization of a negative regulator AveI for avermectin biosynthesis in Streptomyces avermitilis NRRL8165. Appl Microbiol Biotechnol 80(2): 277-86. A six chip study using total RNA recovered from three separate Streptomyces avermitilis NRRL8165 and three separate cultures of a Streptomyces avermitilis NRRL8165 delta-aveI (delta-l) mutant. 3 separate RMA normalizations performed, one for each pair of control and mutant samples.
Date made availableMay 16 2010

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