Additional file 2 of Reconfigured metabolism brain network in asymptomatic microtubule-associated protein tau mutation carriers: a graph theoretical analysis

Additional file 2: Figure S2. Regions of atrophy and hypometabolism in MAPT mutation carriers vs non-carriers. This is additional post-hoc analysis examining the effect size between the two groups with cut-off value defined as >0.8. Decline in gray matter volume of inferior temporal gyrus and inferior frontal gyrus (Triangular part) in MAPT mutation carriers vs non-carriers. Projections of areas with relative hypometabolism of inferior frontal gyrus (Triangular part), and hypermetabolism in interior frontal gyrus (Orbital part) in MAPT carriers compared with non-carriers. Reduced gray matter volume and glucose metabolism are depicted in blue. Increased glucose metabolism is depicted in red.