Additional file 1 of Reconfigured metabolism brain network in asymptomatic microtubule-associated protein tau mutation carriers: a graph theoretical analysis

Additional file 1: Figure S1. Regions of atrophy and hypometabolism. Reduced gray matter volume and glucose metabolism are depicted in blue. Data were analyzed at a height threshold of p < 0.001 and were cluster-level corrected for FWE at p < 0.05. (A) Decline in gray matter volume in MAPT mutation carriers vs non-carriers and bvFTD patients vs controls. (B) Projections of areas with relative hypometabolism in MAPT carriers compared with non-carriers and bvFTD patients compared with controls.